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EPA PROPOSES TESTING PROGRAM TO EVALUATE CHEMICAL EFFECTS ON ENDOCRINE SYSTEM
Release Date: 01/08/99
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FOR RELEASE: FRIDAY, JANUARY 8, 1999
EPA PROPOSES TESTING PROGRAM TO EVALUATE CHEMICAL EFFECTS
ON ENDOCRINE SYSTEM
EPA is seeking comment on a comprehensive, new testing program to help evaluate whether chemicals present in the environment can adversely affect the endocrine systems of humans and wildlife. Initially, the program will focus on some 15,000 chemicals, which are manufactured in volumes exceeding 10,000 pounds annually, and for which existing test data is limited. As a first step toward constructing its program, EPA is proposing to submit these chemicals to a series of high throughput pre-screening (HTPS) assays that have the potential to quickly and efficiently screen chemicals for endocrine activity. Under EPA’s proposed program, chemicals that go through these screening assays and test negative will not need further testing. However, chemicals that test positive may be subjected to a battery of additional tests that will help determine their effects on the reproductive, developmental and behavioral functions of the endocrine system. The schedule for implementing the endocrine disruptor screening program (EDSP) will be phased in over the next several years and is expected to evolve as test methods and standards for identifying the effects of chemicals on the endocrine system are developed. The framework for the program is based on a series of recommendations developed by the Endocrine Screening and Testing Advisory Committee, an independent advisory group of nationally recognized scientists, public health experts and industry representatives assembled by EPA to assist in establishing its EDSP program. A copy of the program is available for public comment on EPA’s website at: www.epa.gov/fedrgstr/EPA-TOX (scroll to Dec. 28, 1998). Hard copies can also be requested through EPA’s TSCA Hotline at 202-554-1404.
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