Computational Toxicology and Exposure Online Resources
EPA's Safer Chemicals program produces a variety of computational tools to assist users in decision-making, researching, and evaluating chemical information. These tools offer a wealth of chemistry, toxicity, and exposure data that is publicly accessible.
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ChemExpo Knowledgebase
The Chemical Exposure Knowledgebase (ChemExpo) is an interactive tool for exploring and searching information on how chemicals are used in commerce and in consumer products.
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Cheminformatics Modules
Cheminformatics analysis modules provide high-quality chemical structures, experimental and predicted physicochemical properties, environmental fate and transport information, and linked toxicity data.
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CompTox Chemicals Dashboard
The CompTox Chemicals Dashboard provides publicly-accessible chemistry, toxicity, and exposure information for over one million chemicals. This information includes physicochemical data, hazard data, and much more.
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GenRA Tool
The Generalized Read-Across (GenRA) tool is an algorithmic approach to permit objective and reproducible read-across predictions of in vivo toxicity and in vitro bioactivity.
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ECOTOX Knowledgebase
The Ecotoxicology (ECOTOX) Knowledgebase is a comprehensive database providing information on adverse effects of single chemical stressors to ecologically relevant aquatic and terrestrial species.
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SeqAPASS Tool
The Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool is a fast, online screening tool that allows researchers and regulators to extrapolate toxicity information across species.
Computational Toxicology and Exposure Informatics Resources
EPA’s computational toxicology research efforts evaluate the potential health effects of thousands of chemicals. Types of available, open-source data include: high-throughput screening, rapid exposure and dose, animal toxicity, chemistry, and virtual tissues.
Access and download computational toxicology and exposure data and application programming interfaces (APIs):